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Global Commercial Operations, Program Manager

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

We're looking for a highly motivated and experienced Staff/Senior Staff, Global Commercial Capabilities Program Manager to join our team. In this pivotal role, you'll be instrumental in shaping the future of our commercial operations by ensuring our systems and processes effectively support our global growth initiatives. You'll bridge the gap between business needs and technical solutions, driving both the initial setup for new product launches and the ongoing evolution of our core commercial systems.

Responsibilities

  • Quarterly Release Management for System Enhancements:
    • Manage the end-to-end release cycle for quarterly system enhancements, focusing on core commercial platforms.
    • Oversee User Acceptance Testing (UAT) processes, coordinating with business stakeholders to ensure thorough testing and validation of new features and functionalities.
    • Develop and execute Organizational Change Management (OCM) strategies to ensure smooth adoption of system changes, including communication plans, training materials, and support frameworks.
    • Facilitate robust stakeholder coordination across various departments (e.g., commercial operations, IT, regional field operations, field teams) to ensure alignment, gather feedback, and resolve issues throughout the release lifecycle.
    • Monitor and report on release progress, risks, and successful deployment, ensuring timely and high-quality delivery of system improvements.

  • Commercial Enablement:
    • Assist in the intake of requirements for new product introductions and other commercial initiatives, collaborating closely with product management, sales, and marketing teams to understand launch strategies and their impact on commercial systems (e.g., CPQ, Opportunity Management).
    • Contribute to the backlog management process for system enhancements, helping to prioritize and refine requirements based on business value and strategic alignment
    • Collaborate with business stakeholders and Commercial Capability Owners to translate high-level requirements into detailed user stories and acceptance criteria, ensuring clarity and readiness for development.
    • Help define and refine process maps and functional specifications to guide system configurations and enhancements.
    • Ensure system designs align with global commercial strategies, optimize user experience, and drive operational efficiency for new offerings.

Qualifications

  • Bachelor's degree in Business Administration, Information Systems, or a related field.
  • 10+ years of experience in program or project management, with a strong focus on commercial operations, sales enablement, or business systems.
  • Proven experience in gathering and translating business requirements into system specifications for platforms such as CPQ, CRM (e.g., Salesforce), or ERP.
  • Demonstrated ability to assist with backlog management and create detailed user stories for system development.
  • Demonstrated expertise in managing system release cycles, including UAT, OCM, and cross-functional stakeholder coordination.
  • Strong understanding of sales processes, product launch lifecycles, and commercial best practices.
  • Exceptional communication, interpersonal, and presentation skills, with the ability to effectively engage and influence stakeholders at all levels.
  • Excellent analytical and problem-solving abilities, with a keen eye for detail and process optimization.
  • Ability to thrive in a fast-paced, dynamic, and globally distributed environment.

Preferred Qualifications

  • Master's degree or relevant certifications (e.g., PMP, Agile Product Owner Certification).
  • Experience with specific CPQ or CRM platforms (e.g., Salesforce CPQ, Oracle CPQ).
  • Familiarity with agile development methodologies.

The estimated base salary range for the Global Commercial Operations, Program Manager role based in the United States of America is: $115,800 - $173,800. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.
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To improve human health by unlocking the power of the genome.

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Full-time, remote
DATE POSTED
July 9, 2025
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