Research Assistant, Immune Monitoring Core Facility

Pay Range

Company Overview

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe. 

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Job Description

Exciting opportunity at Memorial Sloan Kettering Cancer Center!

Are you passionate about ground breaking research and advancing cancer treatment? Our Immune Monitoring Core Facility in the Ludwig Center for Cancer Immunotherapy is seeking a Research Assistant to support immune monitoring of cancer immunotherapy trials, You will perform variety of laboratory procedures in support of immune monitoring of cancer immunotherapy trials, mainly focused on clinical sample testing with validated ELISPOT and flow cytometry assays, clinical sample processing (PBMC isolation from whole blood), developing and validating additional multicolor flow cytometry/ELISPOT assays as needed. Experience with high dimensional flow analysis using data reduction tools would be valuable.

If you’re eager to be part of a world-renowned research institution and make a tangible impact on cancer treatment, apply today!

Role Overview:

• Setting up T cell stimulation/expansion cultures and running single- and potentially multi-analyte ELISPOT assays
• Running multiparameter flow cytometry assays on the BD LSR Fortessa and/or Invitrogen Attune (surface and intracellular staining methods) in support of immune monitoring of cancer clinical trials; developing and validating new flow panels
• Analyzing high dimension data and creating graphs using appropriate software (e.g., FlowJo, Prism) and data visualization tools
• Performing multiplex immunoassays with accuracy & precision for soluble protein biomarker quantitation on the Meso Scale Discovery platform (and possibly Luminex or other immunoassay platforms in the future).
• Running serological assays to measure clinical trial patient antibody responses by ELISA or high content protein microarrays (e.g., CDI Laboratories, Sengenics).
• Supporting clinical sample processing including PBMC and plasma isolation/cryopreservation from whole blood, extraction of TILs from tumor tissue, and assistance in the accurate maintenance of clinical sample inventories for proper sample tracking.
• Researching scientific literature for methods and procedures to identify innovative methodologies for immune monitoring assays; ordering and maintaining laboratory supplies.
• Drafting and adhering to laboratory standard operating procedures for assays and routine methodologies.
• Routine maintenance and operation of a variety of laboratory instruments used to perform sample analyses.
• Following proper safety recommendations and handling procedures for different biological and chemical materials and ensuring others in the laboratory adhere to proper safety procedures.
• Training other laboratory personnel as needed.
• Performing all other duties as assigned.

Key Qualifications:

• B.S. in biology or related field with 4 years of relevant experience (flow cytometry, ELISPOT etc.), or M.S. with 2 years of experience.

Core Skills:

• Exceptional attention to detail and strong analytical skills.
• Ability to thrive in a fast-paced research environment, managing multiple projects while maintaining precision.
• Critical thinking and problem-solving skills to troubleshoot experimental challenges.
• Outstanding interpersonal and communication skills and the ability to interact across all levels in a confident, concise, professional manner.
• Enthusiasm and dedication to MSK's vision, mission and values.

Additional Information:

• Location: Zuckerman, 417 E 68th Street, NYC
• Schedule: 37.5 hours per week (onsite)

Pay Range: $67,900 - $105,300

Helpful Links:

• MSK Compensation Philosophy
• Review our great benefits offerings
• Immune Monitoring Core Facility

Closing

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.  

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