Medicinal Chemistry Senior Research Fellow

Job Description

The Senior Fellow, Lead Chemist for Non-Viral Delivery, has an impressive history of accomplishments which contribute significantly to the advancement of projects and is recognized internally and externally as a thought leader in the design, development, and implementation of non-viral delivery for therapeutic applications. The incumbent applies superior acumen in identifying project needs that are bolstered by refined, systematic creativity and strong judgment of when to launch efforts on a new trajectory. The Lead Chemist for Non-Viral Delivery will define the activities of a chemistry group and will be required to coordinate multiple teams to achieve project goals.

KEY DUTIES and RESPONSIBILITIES 

• Manages activities of the research group across project boundaries 

• Mentors on scientific and ethical development, motivates personnel and resolves conflicts 

• Ensures personnel goal setting is effectively linked to corporate and department goals 

• Oversee activities of staff and adapts personnel deployment to changing priorities, to ensure key goals of all projects are met on time 

• Helps define scientific and strategic directions and develop champions of technological innovation for the research group 

• Directs effective, timely and ethical publication and patenting activities for the group 

• Leads effective management of CRO contracts and/or external scientific collaborations 

• Maintains the excellence of standards for structure and interpretation of all laboratory records, electronic database entries, internal reports, patents, and external communications from the group. 

• Communicates company objectives to the group and availability of group resources and methods to Project Team(s), in a clear and timely manner, and develops abilities of others in this role 

• Leads preparation of lucid scientific reports for all other branches and levels of the organization and its collaborators, presents expertly when called upon to various stakeholders and senior leadership  

• Responsible for developing and cultivating and high achieving organization  

KNOWLEDGE and SKILLS 

• Advanced expertise in state-of-the-art non-viral (e.g. LNP/VLP) delivery technologies for therapeutic applications with a focus on the discovery, development, and implementation of strategies for tissue-specific delivery (expert level) 

• Expertise in lipid design and synthesis including the use of automation
• Deep knowledge in conjugation chemistry to advance drug delivery

• Demonstrated scientific productivity as evidenced by a strong publication record in top tier journals or equivalent industry accomplishment 

• Highly developed scientific leadership qualities and established prowess integrating the activities of distinct functional groups across multiple projects. 

• Greater aptitude for identifying productive new research initiatives/directions 

• Experienced mentor who effectively infuses confidence and team commitment 

• Exhibits a record of excellent operational and ethical standards, and team-improvement 

• Scientifically diverse and effective communicator 

• Possesses greater knowledge of the drug development process and a keener awareness of issues therein 

• Demonstrated success in resolving important organizational problems and/or infusing innovation 

EDUCATION and EXPERIENCE 

• Ph.D. (or equivalent degree) in chemistry with 11+ years of relevant post-doctoral employment experience in medicinal and lipid chemistry. 

• Strong track record of developing non-viral delivery technologies for therapeutic applications. 

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Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com