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Senior Staff Program Manager - Sequencing Platforms

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

This position is primarily an individual contributor role with up to 75% of time spent leading projects/programs starting with the very early phases of research and concept development, up to the full execution of the product development cycle. Projects/programs are typically highly complex with a broad multidisciplinary and/or technical scope.

  • May manage one or more solid-line direct reports and supervise the activities of others in a matrixed environment.
  • Often the point-person between a team of PM’s supporting projects for a business unit.
  • Occasionally provides strategic input and collaboration with the BU.
  • Consistently demonstrates advanced maturity and emotional intelligence.
  • Mentors and develops team members
  • Anticipates internal/external business and regulatory issues
  • Recommends product, process or service improvements and supports their execution
  • Identifies strategic opportunities for the platform or BU and effectively communicates them to executives
  • Acts independently to determine methods and procedures on new or special assignments.

Responsibilities:

  • Primary Project Manager on projects with a multidisciplinary and or technical scope, including platform projects
  • Leads and/or strongly contributes to project definition
  • Leads the project planning activities including identification of keys task and formulation of timelines
  • Develops project plans, including detailed timelines with durations, dependencies, critical path, and milestones
  • Provides management and leadership skills and drives execution on program goals.
  • Works on simple to complex challenges Interprets internal/external business and regulatory challenges and recommends best practices to improve products, processes or services.
  • Determines methods and procedures on new assignments and coordinates activities of other personnel.

Requirements:

  • Command of product development lifecycles
  • Comfortable applying the principles of Design For Six Sigma
  • Command of most topics in the PM Body Of Knowledge (PMBOK)
  • Expert at project scheduling using MS Project, including dependencies and critical path determination and optimization
  • Knowledge of genetic sequencing principles
  • Ability to operate at a system level as well as dig deep into specifics
  • Experienced in product development of advanced technology projects, understands very well how to manage cross functional deliverables of high complexity
  • Ability to manage the interaction between software, hardware, chemistry on a sequencer.
  • Able to transform data into actionable information
  • Ability to communicate effectively at all levels of the organization.
  • Demonstrates good judgment in selecting methods and techniques for obtaining solutions.
  • Ability to network with senior internal and external personnel in own area of expertise.
  • Requires a minimum of 10-12 years of product development experience in a regulated industry with 6 years managing projects.

Experience/Education:

  • Typically requires a minimum of 12 years of related experience with a Bachelor’s degree; or 8 years and a Master’s degree; or a PhD with 5 years experience; or equivalent experience
  • Typically requires a current PMP certification
  • A technical background in engineering, advanced science or equivalent is a must have for this role

#LI-HYBRID

The estimated base salary range for the Senior Staff Program Manager - Sequencing Platforms role based in the United States of America is: $152,600 - $228,800. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.
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Average salary estimate

$190700 / YEARLY (est.)
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$152600K
$228800K

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To improve human health by unlocking the power of the genome.

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Full-time, hybrid
DATE POSTED
July 9, 2025
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